Natrona County is a county in the state of Wyoming, United States. According to the 2020 U.S. Census, the county has a population of 79,955, making it the second most populous county in Wyoming. The county seat is Casper, a region with a wealth of natural and cultural attractions. Natrona County includes the Casper metropolitan area.
Located on Wyoming's Highway 220, Independence Rock is a national treasure and state historic site, known as the "register of the desert." It's a significant landmark for pioneers as they journeyed west on the Oregon Trail, the Mormon Trail, and the California Trail, with over 5,000 early settlers having their names inscribed here.