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Knox County Tennessee ☎ +1 865-215-2005 Last Updated: 06/10/2025 |
| Knox County is a county located in the U.S. state of Tennessee. The population was 500,669 as of a 2023 estimate, making it the third-most populous county in Tennessee. Its county seat is Knoxville, The county is at the geographical center of the Great Valley of East Tennessee. Near the heart of the county is the origin of the Tennessee River at the union of the Holston and French Broad Rivers. | |